Brain has sixth sense for calories
The brain has a way of sensing calories in food, independent of the taste mechanism, according to a new study. The discovery that the brain's reward system is switched on by this "sixth sense" machinery could have implications for understanding the causes of obesity. For example, the findings suggest why high-fructose corn syrup, widely used as a sweetener in foods, might contribute to obesity. Findings of the study have been published in the latest issue of the journal Neuron. Ivan de Araujo and his research colleagues genetically altered mice to make them "sweet-blind", or lacking a key component of taste receptor cells that enabled them to detect the sweet taste. The researchers next performed behavioural tests in which they compared normal and sweet-blind mice in their preference for sugar solutions and those containing the non-caloric sweetener sucralose. In those tests, the sweet-blind mice showed a preference for calorie containing sugar water that did not depend on their ability to taste, but on the calorie content. In analysing the brains of the sweet-blind mice, researchers showed that the animals' reward circuitry was switched on by caloric intake, independent of the animals' ability to taste. Those analyses showed that levels of the brain chemical dopamine, known to be central to activating the reward circuitry, increased with caloric intake. Also, electrophysiological studies showed that neurons in the food-reward region, called the nucleus accumbens, were activated by caloric intake, independent of taste.
Link Times of India
Friday, March 28, 2008
Sunday, March 9, 2008
Treating patients with bacteria may be an effective way of reducing their risk of repeatedly developing painful kidney stones, a study suggests.
People naturally carrying the bacterium Oxalobacter formigenes were found to be 70% less likely to have problems.
Researchers at Boston University, in the US, are now investigating the possibility of using the bacteria as a "probiotic" treatment.
The study features in the Journal of the American Society of Nephrology.
Kidney stones are small, hard lumps formed of waste products contained in the urine.
They normally range in size from a grain of sand to a pearl. They can be smooth or jagged, and are usually yellow or brown.
Once a kidney stone has formed in a kidney it may travel down through the other parts of the urinary system, where they can slow the flow of urine, cause infection, severe pain and even lead to kidney failure.
About three in 20 men and one in 20 women in the UK will develop a kidney stone at some point in their lifetime.
They are most likely to occur in people aged 20 to 40.
Up to 80% of kidney stones are predominately composed of a compound called calcium oxalate.
O. formigenes breaks down oxalate in the intestinal tract and is present in a large proportion of the normal adult population.
The Boston team compared 247 patients with recurrent calcium oxalate kidney stones with 259 people with no history of the condition.
They found just 17% of the kidney stones group were colonised with O. formigenes, compared with 38% of healthy group.
Researcher Professor David Kaufman: "Our findings are of potential clinical importance.
"The possibility of using the bacterium as a probiotic is currently in the early stages of investigation."
Promising avenue
Derek Machin, clinical director of urology at University Hospital, Aintree, said an effective treatment for recurrent kidney stones would be a significant step forward.
He said bigger kidney stones were currently treated by using shock waves to break them up, but this was not always completely effective.
Passing a stone in the urine intact can be extremely painful, and even getting rid of the smaller pieces created by shock treatment could cause significant pain.
"For some people kidney stones can be an on-going lifelong problem," he said.
"And in some cases a stone can destroy kidney function before it is even identified."
However, Mr Machin warned that there was much work to be done before clinical trials of a probiotic could be considered.
He said kidney stones had been linked to dehydration and were more common in countries such as Saudi Arabia where the climate is hot and dry.
In instances they may be linked to an unusually high rate of calcium excretion.
However, he said in many cases there was no obvious cause for the condition. It is a particular problem for airline pilots, who are not allowed to fly if they have a stone.
Thursday, March 6, 2008
Kerala’s booming Ayurveda industry is opening up employment opportunities for many women.
Every morning, serpentine queues form outside Vaidyaratnam Oushadhasala, an Ayurveda centre in Trichur district. Women from the nearby Thykattussery village supply fresh milk to the centre, which is used for manufacturing medicines. Over 200 women in the village have invested in milk cows. “The milk required by the Oushadhasala has to be of very good quality so we have invested in cows. I started with one cow, now I have three. I supply milk to the centre the year round. The cows are fed properly and kept in clean surroundings. They also undergo regular veterinary check-ups. The Oushadhasala is a confirmed customer and we make good money,” says Girija, 40, whose mother and sisters have joined her in the venture. After testing the milk for purity, the Oushadhasala buys around 700 litres daily at a competitive rate of Rs 11 per litre.Source of income
Before they started deriving economic benefit from the Ayurveda centre, most women in Thykattussery either worked as domestic help or farm labourers. However, now the milk business gives them a steady income. Girija’s sister, Rati, 26, says, “We took a loan from the lady of the house where Girija used to work as a domestic help to buy our first cow. But the next two cows were bought from the profits made by selling the milk.”
Centres like the Vaidyaratnam Oushadhasala play a huge role in the economic development of the area and thousands of women are piggy-backing this wave of prosperity. Doctors, nurses and masseuses head the list of qualified professionals that have found favour with the industry. Massage training
Dr Ambika Rahulan, 56, joint owner of Aswathy Bhavan Vaidyasala in Tiruvalla, says that while doctors and nurses require relevant degrees, masseuses can enrol for a six-month training course the centre offers, during which they are paid a stipend. “After completing the course, the women are qualified to start a massage unit of their own or join any centre or hotel as masseuses.”
“Besides those qualified to work in this sector, there is a large section of marginally educated women who take home a decent pay packet.” About 500 rural women, living mostly in forest and hill regions like Amdallur, Velikulangara and Peachy, are involved in collecting herbs for our pharmaceutical wing,” says T. Unnikrishnan, General Manager, Vaidyaratnam Oushadhashala.
“We impart preliminary knowledge to the women on the herbs we need at the lab. While some are natural, having lived amidst these plants throughout their lives, others are taught.” “We collect herbs like tulsi, kuruntoti and ketakamuladi , which are easily available. Depending on the herb, we are paid Rs 15 per kg. For example, a kg of Kuruntoti would fetch Rs 40. Many of us also have herb gardens where we plant the common herbs and then sell them,” says Thallur-based Lalita Srinivasan. Women look for herbs in the fields, forests and farms. At times, they even offer landowners a nominal fee for permission to collect herbs. They begin work early in the morning and sell the herbs to the Ayurveda centres by 4 p.m. every day.
“I studied only till Class IV. There were no job opportunities for me. My husband is a heart patient and is unable to work. I have two children. I earn about Rs 2,000 every month collecting and selling herbs like unnginver and chanakayanga ,” says Lalitha. High returns
Kanakamma, 28, from Marathakkara, cautions, “One has to be a regular to make good money. My mother did it for 30 years and now I am doing it. I have planted a herb garden near my house with an investment of Rs 5,000 and it has given me excellent returns.”
Other than those collecting herbs, there are women who sift and clean the collection for a daily wage of about Rs 70 to Rs 100. Susheela, 34, from Cherp, works as a contractual labourer and manages to earn around Rs 1,800 per month. “Some herbs take more time and effort to clean. We are paid more for such difficult tasks. Chuk or dry ginger is easier to clean so we do it in large quantities to make more money. This is the kind of work where the lack of education does not matter. I have only studied till Class III. Where else would I find work? My husband doesn’t work. I have to feed my children.”
Packaging units, where medicines and other products are made market-ready, are also popular avenues of employment. A.M. Sreedevi, 54, who has studied till class 10, works at the Oushadhasala’s packaging unit as a permanent employee. “It was unheard of in my family for women to work. However, when we were faced with financial difficulties, I started looking for work. The Ayurveda drugs packaging unit here was perfect. I joined in 1973. It is a comfortable working environment and there is no physical toil. I get basic pay, dearness allowance, washing allowance and incentives,” she says.
Shanta, 51, who joined in 1993, adds, “We work in shifts and the pay is good. We also get overtime. With an education up to Class III only, what more could I have expected? I am earning about Rs 4,000 to Rs 5,000 every month.”
Monday, September 10, 2007
Junk food with less health risks soon!
Hamburgers and drinks may soon come to be marketed with reduced risk of heart disease and deep-vein thrombosis as their USP.
The Australian research body CSIRO (Commonwealth Scientific and Industrial Research Organisation) is developing some of such "super-foods", which they claim have medical benefits.
The functional foods will come up for discussion at an international food safety conference, to be held this month in
Food Standards Australia New Zealand (FSANZ), a governmental body responsible for developing food standards for
The standards body will detail its plans at the second Food Safety Conference, New Directions 2007, to be held on September 19-21.
Lydia Buchtmann, the spokeswoman for FSANZ, admits that it is illegal to make any "high-level" health claims of food, such as its reducing the risk of cancer or heart disease. She, however, claims that many products are "sailing pretty close to the wind" with general health claims.
She says that the only exception to the laws is folic acid, which is proven to decrease the risk of having a baby with spina bifida.
"Functional foods are moving from food that fills you up and are good for you to something that will prevent cancer and urinary tract infection (for example)," the Sydney Morning Herald quoted Buchtmann as saying.
She says that foods claimed to be low in saturated and tarns fats, or fruits and vegetables said to decrease the risk of heart disease, are likely to get the legal nod. But, she adds, any association between eating fruit and vegetables and reduction in the risk of cancer will not be approved because it lacks evidence.
According to Buchtmann, general health claims like sugarless products promoting dental health or cranberry juice assisting recovery from urinary tract infection or calcium intake improving bone strength may be legalised.
Manufacturers must have scientific proof, and the food's ingredients will be put through a computerised "nutrient profiler" to measure good and bad ingredients.
Dr. Bruce Lee, the director of CSIRO Food Futures who will speak at the conference, said that scientists were working on developing a glycoprotein with a "satiating effect" and potential to control weight.
Other additives with a health benefit above nutrition include an "anti-thrombic" ingredient to help prevent deep-vein thrombosis, a glucosamine/chondroitin-like compound to help prevent arthritis, and an antioxidant from Australian native fruits to combat the effects of ageing, he said.
He also said that scientists were researching how to make tasty, healthy, high-energy foods.
"It would be to take a hamburger that tastes like a hamburger, will give you the same eating experience, but doesn't give you all the calories we hope that this will happen in the next five years," he said.
Dr. Lee said that scientists could achieve their object by using "fat replacers" such as a modified protein, perceived to have the same taste properties as saturated fat but without any harmful effects.
Thursday, August 23, 2007
Ways to increase and maintain the quantity of the drinking water.
Keep a Log This can be as simple as a little piece of paper on the fridge, or a page in your day planner. Just make a little checkmark, or dash on the piece of paper every time you drink a glass of water. The log will help you keep track of how much water you have had in any given day. You'll also be surprised at how motivating it is to try to get those eight little checkmarks on there every day. Another idea would be to use little stickers instead. Add Some lemon juice One tends to get bored with drinking just water after a few days. Change things up and add a little flavour by adding a teaspoon or less of lemon to your water. You can also try some other fruit juices. Carry a water bottle It's much easier to drink water when you have it readily available. Carry a bottle of water around with you in the car, at work, while running errands, in the yard, and even while you are working around the house. You'll be sipping away the water without even noticing it. Your body will thank you for it in the long run.
Tuesday, August 21, 2007
Link timesofindia
Sunday, July 15, 2007
Friday, April 13, 2007
Asian News international
No matter how much weight you loose dieting, it will always come back, warn researchers.
And, to make matters worse for people who keep going on diets to get rid of those extra pounds, the researchers also warn that when the weight comes back, it’s highly likely that you will be a few kilos heavier that you were before you went on the diet.
The study was conducted by researchers at the University of California, Los Angeles, led by Traci Mann, UCLA associate professor of psychology.
Mann insisted that though dieting could see a persons weight drop by 5 to 10 percent, the loss was not sustainable in most cases.
"You can initially lose 5 to 10 per cent of your weight on any number of diets, but then the weight comes back. We found that the majority of people regained all the weight, plus more," she said.
"Sustained weight loss was found only in a small minority of participants, while complete weight regain was found in the majority. Diets do not lead to sustained weight loss or health benefits for the majority of people," Mann added.
The researchers, whose findings are based on an analysis of 31 long-term diet studies, found that while people on diets typically lose 5 to 10 percent of their starting weight in the first six months, at least one-third to two-thirds of people on diets regain more weight than they lost within four or five years, and the true number may well be significantly higher.
"Although the findings reported give a bleak picture of the effectiveness of diets, there are reasons why the actual effectiveness of diets is even worse," Mann said.
The researchers also noted that certain factors biased the diet studies to make them appear more effective than they really were. For one, many participants self-reported their weight by phone or mail rather than having their weight measured on a scale by an impartial source.
Also, the studies have very low follow-up rates — eight of the studies had follow-up rates lower than 50 percent, and those who responded may not have been representative of the entire group, since people who gain back large amounts of weight are generally unlikely to show up for follow-up tests.
"Several studies indicate that dieting is actually a consistent predictor of future weight gain," said Janet Tomiyama, a UCLA graduate student of psychology and co-author of the study.
One study, which examined a variety of lifestyle factors and their relationship to changes in weight in more than 19,000 healthy older men over a four-year period, found that "one of the best predictors of weight gain over the four years was having lost weight on a diet at some point during the years before the study started," Tomiyama said.
So if dieting doesn't work, then the question becomes - what does? The answer is eating in moderation and getting regular exercise.
"Eating in moderation is a good idea for everybody, and so is regular exercise. That is not what we looked at in this study. Exercise may well be the key factor leading to sustained weight loss.
Studies consistently find that people who reported the most exercise also had the most weight loss," Mann said.
Evidence suggests that repeatedly losing and gaining weight is linked to cardiovascular disease, stroke, diabetes and altered immune function.
The researchers now recommend that more research be conducted on the health effects of losing and gaining weight, noting that scientists do not fully understand how such weight cycling leads to adverse health effects.
Saturday, April 7, 2007
Victims of chronic back pain were offered fresh hope with news of successful”spinal transplant”surgery. Spinal discs from accident victims were transplated into patients with disc degeneration in the cervical spine,the area nearest the neck. All reported improvements in their mobility and areduction in symptoms such as weakness of legs and bladder.
A report in Lancent says the pioneering treatment carried out in China offers hope for thousands of sufferers of severe disc problems particularly young people.
The disc transplantation was carried out by doctors at the Navy General Hospital, Beijing and the University of Hongkong. Although disc transplants have been carried out in primates, it is first time doctors have reported such surgery in humans. The Chinese doctors used 13 discs, which were frozen and thawed out prior to transplant. With in three months, the donor discs had successfully bedded in with existing spinal disc tissue.
Wednesday, April 4, 2007
Danish team converts A, B and AB into type O
Times of India April 3, 2007writes
The blood group barrier set to come down. In a break through that can make all humans universal donars. Danish scientists have successfully converted A,B and AB blood type into type O, the universal donar blood which can begiven to any one in need of a transfusion.
The inexpensive and efficient technique involves isolating bacterial glycosidase enzymes the safely remove sugar molecules from red blood cells(RBC).RBCs havecomplex sugars on their surfaces that determine the blood type.
Link Times of India.com
Saturday, March 31, 2007
Washington: A new research has revealed that women in their 70s who keep active could escape painful arthritis symptoms. The research was conducted by Kristiann Heesch and colleagues at the University of Queensland, Australia. As part of the research data on middle-aged (48-55) and older (72-79) women was collected using surveys over three years as part of the Australian Longitudinal Study on Women's Health. Women who reported arthritis symptoms at the beginning of the study were excluded, and the authors examined those who began reporting stiff or painful joints 'often' and the amount of exercise they undertook. Researchers found that for women in the older age bracket, a little over an hour of moderate physical activity each week will lessen the chances of developing frequent arthritis symptoms in the next three years. Pushing that up to 2 ½ hours per week is even more likely to prevent arthritis symptoms appearing. These results were not seen for the middle-aged group. Exercising into old age could ensure movement without stiffness and pain for longer, and could reduce the burden of arthritis on the healthcare system. The research was published in Arthritis Research & Therapy.
Link India times
Friday, February 23, 2007
If you invest in Good health, Wealth follows........
Invest now in improved health in the developing world, and you will reap massive returns later.
"If you invest in health, you increase economic growth and economic development," Dr Brundtland said. And this, she argued, is true both for companies motivated by profits and for struggling nations trying to escape poverty.
"Enlightened self interest compels both industrialised country governments and private corporations to do what it takes to drastically reduce the current burden of disease in the developing world," Dr Brundtland said. Healthy workers are efficient workers .
"The people that you have as your staff in your company are of course an investment. You train them, you need them. If they are healthy, they will be at work and they will be more productive," Dr Brundtland reasoned.
"So in the same way that you invest in machines and technology and other goods that create your wealth, you certainly have to invest in the people that you have as your staff".
Personnel managers in the political West, which comprises the rich countries in the world, have known this for a long time. Now, says Dr Brundtland, the message is beginning to reach companies in Africa, South America and Asia as well. Many European and US companies operating in these regions are beginning to invest in their staff, in their staff's families, and in the communities in which they work, she said.
"A healthy environment and more healthy staff is an asset for the company. Not only for their image, but even in more complete terms in the way they are able to make profits," Dr Brundtland said.

